Common Presentations of Mycosis Fungoides in Pakistani Population: A Clinicopathological Study

Authors

  • Humaira Talat Department of Dermatology, Dr Ruth KM Pfau Civil Hospital, Karachi and Dow University of Health Sciences, Karachi, Pakistan
  • Erum Ashraf Department of Dermatology, Dr Ruth KM Pfau Civil Hospital, Karachi and Dow University of Health Sciences, Karachi, Pakistan.
  • Sana Siddiqui Department of Dermatology, Dr Ruth KM Pfau Civil Hospital, Karachi and Dow University of Health Sciences, Karachi, Pakistan
  • Zarnaz Wahid Department of Dermatology, Dr Ruth KM Pfau Civil Hospital, Karachi and Dow University of Health Sciences, Karachi, Pakistan
  • Deepa Mohan Lal Department of Dermatology, Dr Ruth KM Pfau Civil Hospital, Karachi and Dow University of Health Sciences, Karachi, Pakistan

Keywords:

Mycosis fungoides, Cutaneous T cell Lymphoma, Sezary syndrome, Erythroderma

Abstract

Objective: To study the different clinical, pathological and immunophenotypic features in patients of Mycosis fungoides presenting to Civil Hospital Karachi.
Methods: A case series consisting of 10 patients was conducted at the Dermatology department of Civil Hospital Karachi, from January 2013 to December 2016.A Performa was used after written consent from the patients and the head of the department to record the history, physical examination and laboratory findings.
Results: Out of the 10 patients, 3 had stage IIB, 3 had stage III, 1 patient evolved from stage III to IV and 3 had stage IV disease, 2 patients were in erythrodermic stage, while 1 evolved from the erythrodermic stage to the tumor stage. 3 patients showed psoriasiform appearance, 3 showed tumor d emblee stage, while only 1 patient revealed poikilodermatous appearance. Male to female ratio was 5:1. Histopathological and immunophenotypic markers were consistent with those of mycosis fungoides.
Five patients were previously treated as eczema or psoriases.
Conclusion: Knowledge about the varied presentations of mycosis fungoides would lead to better understanding, and help us with the diagnostic challenges in our population.

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References

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Published

2017-12-19

How to Cite

Talat, H., Ashraf, E., Siddiqui, S., Wahid, Z. ., & Lal, D. M. (2017). Common Presentations of Mycosis Fungoides in Pakistani Population: A Clinicopathological Study. Journal of the Dow University of Health Sciences (JDUHS), 11(3), 103–105. Retrieved from https://jduhs.jduhs.duhs.edu.pk/index.php/jduhs/article/view/1367

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Section

Case Series